Applications for Small Volume Parenterals include local anesthetics, vaccines, and other traditional injectable products. The 10 to 100 mL range is typically designed for multi-dose applications.
A simple twist-off opening feature can be combined with a controlled diameter formed in the top to accommodate needle-less spikes. Alternatively, a luer lock or luer slip can be provided. Bottles can be designed with folding, integral hangers. 0.1 Ml Syringe
Small Volume Parenterals in the 2 to 5 mL range most commonly utilize a luer lock or luer slip fit (vented luer) top geometry. Syringes can be connected directly to the ampoules without a needle, creating an inherently safer delivery method.
A syringe with a needle can also be used, since a larger percentage of the smaller ampoules are used to provide diluent to reconstitute lyophilized drugs.
Large Syringe 100ml Top geometries for small volume parenteral bottle/ampoule sizes of 100 mL or less can include a multi-entry rubber stopper or controlled diameter, injection molded insert (combined with Weiler's insertion technology). These designs are useful where multiple administration of a drug is required.